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style=\"font-weight: 400\">\u5e0c\u68ee\u7f8e\u5eb7\u548c\u536b\u6750\u6b63\u5728\u52aa\u529b\u521b\u5efa\u65b0\u7684\u7528\u4e8e\u9884\u9632\u548c\u6cbb\u7597\u75f4\u5446\u7684\u8bca\u65ad\u6280\u672f\u3002\u56e0\u6b64\uff0c\u9996\u8981\u76ee\u6807\u662f\u4fc3\u8fdb\u533b\u7597\u4fdd\u5065\u7684\u8fdb\u6b65\uff0c\u63d0\u9ad8\u75f4\u5446\u60a3\u8005\u53ca\u5176\u5bb6\u5c5e\u7684\u751f\u6d3b\u8d28\u91cf\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u672f\u8bed<\/strong><\/p>\n<p style=\"font-weight: 400\">1\u00a0\u4e00\u4e2a\u6807\u51c6\u5316\u91cf\u8868\uff0c\u7528\u4e8e\u5bf9\u4e0d\u540c\u6dc0\u7c89\u6837\u86cb\u767dPET\u6210\u50cf\u63a2\u9488\u6d4b\u91cf\u7684PET SUVR\u503c\u8fdb\u884c\u7efc\u5408\u5206\u6790\u3002<\/p>\n<p style=\"font-weight: 400\">2\u00a0\u7ecf\u8fc7\u57f9\u8bad\u7684\u533b\u751f\u901a\u8fc7\u89c6\u89c9\u8bfb\u7247\uff0c\u53ef\u5b9a\u6027\u9274\u522b\u6dc0\u7c89\u6837\u86cb\u767dPET\u9633\u6027\u53d7\u8bd5\u8005\u548c\u6dc0\u7c89\u6837\u86cb\u767d\u9634\u6027\u53d7\u8bd5\u8005\u3002<\/p>\n<p style=\"font-weight: 400\">3 Klunk WE\u00a0<em>et al,<\/em>\u00a0Alzheimer\u2019s Dementia (2014)<\/p>\n<p style=\"font-weight: 400\">4\u00a0\u57fa\u4e8e\u4e24\u4e2a\u5b9a\u91cf\u6570\u636e\u5206\u5e03\u8bc4\u4f30\u4e24\u7ec4\u6570\u636e\u7684\u76f8\u5173\u6027\u3002\u4e3a\u4e86\u8fdb\u884c\u672c\u5206\u6790\uff0c\u8ba1\u7b97\u4e86Spearman\u79e9\u76f8\u5173\u7cfb\u6570\uff08r<sub>s<\/sub>\uff09\uff0cr<sub>s<\/sub>\u662f\u7531\u4e24\u4e2a\u53d8\u91cf\u7684\u79e9\u6b21\u786e\u5b9a\u7684\u4e00\u4e2a\u76f8\u5173\u6307\u6570\u3002<\/p>\n<p style=\"font-weight: 400\">5 Schindler SE\u00a0<em>et al,<\/em>\u00a0Neurology (2019)<\/p>\n<p style=\"font-weight: 400\">6 2018\u5e74\u4e16\u754c\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u62a5\u544a<\/p>\n<p style=\"font-weight: 400\">7\u00a0\u75f4\u5446\u7efc\u5408\u63aa\u65bd\u7684\u63a8\u5e7f\uff0c\u65e5\u672c\u539a\u751f\u52b3\u52a8\u7701<\/p>\n<p style=\"font-weight: 400\">8\u00a0\u65e5\u672c\u75f4\u5446\u7ecf\u6d4e\u5f71\u54cd\u7814\u7a76\uff0c2014\u5e74\u536b\u751f\u52b3\u52a8\u79d1\u5b66\u7814\u7a76\u8865\u52a9\u5e74\u5ea6\u62a5\u544a<\/p>\n<p style=\"font-weight: 400\">9\u00a0\u5e0c\u68ee\u7f8e\u5eb7\u6839\u636e\u65e5\u672c\u4e2d\u671f\u7ecf\u6d4e\u5c55\u671b\uff082018\u5e742\u6708\uff09\u4f30\u7b97\uff0c\u65e5\u672c\u5927\u548c\u7814\u7a76\u6240<\/p>\n<p>10 A\u03b2\u662f\u7531\u6dc0\u7c89\u6837\u524d\u4f53\u86cb\u767d\u5207\u9664\u7684\u6c28\u57fa\u9178\u6b8b\u57fa\u7ec4\u6210\u7684\u80bd\u3002\u5176\u4e2d\u8bb8\u591a\u662f\u753140\u4e2a\u6b8b\u57fa\u7ec4\u6210\u7684A\u03b2<sub>1-40<\/sub>\uff0c\u5176\u6c34\u5e73\u4e0d\u4f1a\u968f\u7740AD\u7684\u8fdb\u5c55\u800c\u660e\u663e\u6ce2\u52a8\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u753142\u4e2a\u6b8b\u57fa\u7ec4\u6210\u7684A\u03b2<sub>1-42<\/sub>\u5177\u6709\u9ad8\u805a\u96c6\u6027\uff0c\u8111\u810a\u6db2\uff08CSF\uff09\u4e2d\u7684A\u03b2<sub>1-42<\/sub>\u4eceAD\u65e9\u671f\u5c31\u5f00\u59cb\u51cf\u5c11\u3002\u8ba4\u4e3aA\u03b2\u7684\u7edd\u5bf9\u503c\u8868\u73b0\u51fa\u4e2a\u4f53\u548c\u5185\u5728\u53d8\u5f02\u6027\uff0c\u4f46\u8840\u6d46A\u03b2<sub>1-42<\/sub>\/A\u03b2<sub>1-40<\/sub>\u6bd4\u503c\u4fdd\u6301\u4e0d\u53d8\u3002\u636e\u62a5\u9053\uff0cCSF\u4e2dA\u03b2<sub>1-42<\/sub>\/A\u03b2<sub>1-40<\/sub>\u6bd4\u503c\u4e0e\u6dc0\u7c89\u6837\u86cb\u767dPET\u9ad8\u5ea6\u76f8\u5173\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><b><strong style=\"font-style: inherit\">\u5173\u4e8e\u5e0c\u68ee\u7f8e\u5eb7\u4e0e\u536b\u6750\u7684\u5408\u4f5c<\/strong><\/b><br \/>\n2016\u5e742\u6708\uff0c\u5e0c\u68ee\u7f8e\u5eb7\u548c\u536b\u6750\u7b7e\u7f72\u4e86\u4e00\u9879\u5168\u9762\u7684\u975e\u6392\u4ed6\u6027\u534f\u8bae\uff0c\u65e8\u5728\u4e3a\u75f4\u5446\u9886\u57df\u5f00\u53d1\u65b0\u7684\u8bca\u65ad\u68c0\u6d4b\u3002\u4e24\u5bb6\u516c\u53f8\u5728\u6280\u672f\u548c\u77e5\u8bc6\u65b9\u9762\u5f7c\u6b64\u501f\u529b\uff0c\u5171\u540c\u81f4\u529b\u4e8e\u7814\u53d1\u65b0\u4e00\u4ee3\u7684\u8bca\u65ad\u8bd5\u5242\uff0c\u4ee5\u4fbf\u80fd\u591f\u65e9\u671f\u8bca\u65ad\u75f4\u5446\u3001\u9009\u62e9\u6700\u5408\u9002\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u5e76\u5b9a\u671f\u76d1\u6d4b\u6b64\u7c7b\u6cbb\u7597\u7684\u6548\u679c\u3002\u57282019\u5e7412\u6708\u4e3e\u884c\u7684\u7b2c12\u5c4aCTAD\u4e0a\uff0c\u4e24\u5bb6\u516c\u53f8\u62a5\u544a\u4e86\u4f7f\u7528\u5168\u81ea\u52a8\u514d\u75ab\u5206\u6790\u7cfb\u7edfHISCL\u6d4b\u91cf\u7684\u8840\u6d46A\u03b2\u6bd4\u503c\u9884\u6d4b\u6dc0\u7c89\u6837\u86cb\u767dPET\u626b\u63cf\u7ed3\u679c\u7684\u6027\u80fd\uff08\u654f\u611f\u6027\uff1a73%\uff0c\u7279\u5f02\u6027\uff1a71% [AUC=0.74]\uff09\uff0c\u7ed3\u679c\u8bc1\u660e\u4e86\u4f7f\u7528\u8840\u6d46A\u03b2\u6bd4\u503c\u9884\u6d4b\u8111\u6dc0\u7c89\u6837\u75c5\u7406\u7684\u6f5c\u529b*\u3002\u8fd9\u4e00\u53d1\u73b0\u6709\u671b\u5f00\u53d1\u4e00\u79cd\u7528\u8840\u6db2\u8bca\u65ad\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u7b80\u5355\u65b9\u6cd5\u3002<\/p>\n<p>*https:\/\/www.sysmex.co.jp\/en\/news\/2019\/191209.html<br \/>\nhttps:\/\/www.eisai.com\/news\/2019\/news201990.html<\/p>\n<p>&nbsp;<\/p>\n<p><b><strong style=\"font-style: inherit\">\u54a8\u8be2\u8054\u7cfb<\/strong><\/b><br \/>\nIR\u548c\u4f01\u4e1a\u5ba3\u4f20\u90e8\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u516c\u5171\u5173\u7cfb\u90e8<br \/>\n\u5e0c\u68ee\u7f8e\u5eb7\u96c6\u56e2\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0 \u00a0 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