{"id":5660,"date":"2021-11-01T18:39:42","date_gmt":"2021-11-01T10:39:42","guid":{"rendered":"https:\/\/www.9-design.net\/?p=5660"},"modified":"2021-11-01T18:44:09","modified_gmt":"2021-11-01T10:44:09","slug":"%e7%94%b1%e5%8d%ab%e6%9d%90%e5%92%8cprism-biolab%e5%85%b1%e5%90%8c%e5%bc%80%e5%8f%91%e7%9a%84creb%e7%bb%93%e5%90%88%e8%9b%8b%e7%99%bd%ef%bc%88cbp%ef%bc%89-%ce%b2-%e8%bf%9e%e7%8e%af%e8%9b%8b%e7%99%bd","status":"publish","type":"post","link":"https:\/\/www.9-design.net\/2021\/11\/01\/%e7%94%b1%e5%8d%ab%e6%9d%90%e5%92%8cprism-biolab%e5%85%b1%e5%90%8c%e5%bc%80%e5%8f%91%e7%9a%84creb%e7%bb%93%e5%90%88%e8%9b%8b%e7%99%bd%ef%bc%88cbp%ef%bc%89-%ce%b2-%e8%bf%9e%e7%8e%af%e8%9b%8b%e7%99%bd\/","title":{"rendered":"\u7531\u536b\u6750\u548cPRISM BioLab\u5171\u540c\u5f00\u53d1\u7684CREB\u7ed3\u5408\u86cb\u767d\uff08CBP\uff09\/\u03b2-\u8fde\u73af\u86cb\u767d\u6291\u5236\u5242E7386\u53d6\u5f97\u4e34\u5e8aPOC\uff08\u6982\u5ff5\u9a8c\u8bc1\uff09"},"content":{"rendered":"<p>\u536b\u6750\u682a\u5f0f\u4f1a\u793e\uff08\u603b\u90e8\uff1a\u4e1c\u4eac\uff0c\u9996\u5e2d\u6267\u884c\u5b98\uff1a\u5185\u85e4\u6674\u592b\uff0c\u201c\u536b\u6750\u201d\uff09\u548c<span lang=\"en-US\"> PRISM BioLab Co.<\/span>, <span lang=\"en-US\">Ltd.<\/span>\uff08\u603b\u90e8\uff1a\u795e\u5948\u5ddd\uff0c\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\uff1a<span lang=\"en-US\">Dai Takehara<\/span>\uff0c\u201c<span lang=\"en-US\">PRISM<\/span>\u201d\uff09\u5ba3\u5e03\uff0c<span lang=\"en-US\">CREB-<\/span>\u7ed3\u5408\u86cb\u767d\uff08<span lang=\"en-US\">CBP<\/span>\uff09<span lang=\"en-US\">\/<\/span>\u03b2<span lang=\"en-US\">&#8211;<\/span>\u8fde\u73af\u86cb\u767d\u6291\u5236\u5242<span lang=\"en-US\">E7386<\/span>\uff0c\u536b\u6750\u548c<span lang=\"en-US\">PRISM<\/span>\u5408\u4f5c\u7814\u7a76\u53d1\u73b0\u7684\u4e00\u79cd\u4e2d\u7b49\u5206\u5b50\u91cf\u5316\u5408\u7269\uff0c\u53d6\u5f97\u4e34\u5e8a<span lang=\"en-US\"> POC<\/span>\uff08\u6982\u5ff5\u9a8c\u8bc1\uff09\u3002<span lang=\"en-US\">\u00a0<\/span><\/p>\n<p>\u536b\u6750\u6b63\u5728\u8fdb\u884c<span lang=\"en-US\">E7386<\/span>\u5355\u836f\u6cbb\u7597\u5b9e\u4f53\u7624\u7684<span lang=\"en-US\">I<\/span>\u671f\u4e34\u5e8a\u7814\u7a76\u548c<span lang=\"en-US\">E7386 <\/span>\u8054\u5408\u7532\u78fa\u9178\u4ed1\u4f10\u66ff\u5c3c\uff08\u4ea7\u54c1\u540d\u79f0\uff1a\u4e50\u536b\u739b<span lang=\"en-US\">\u00aeLENVIMA\u00ae<\/span>\uff0c\u201c\u4ed1\u4f10\u66ff\u5c3c\u201d\uff09\u7684<span lang=\"en-US\">Ib<\/span>\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8be5\u836f\u662f\u536b\u6750\u539f\u7814\u7684\u53e3\u670d\u591a\u9776\u70b9\u916a\u6c28\u9178\u6fc0\u9176\u53d7\u4f53\u6291\u5236\u5242\uff0c\u7528\u4e8e\u5b9e\u4f53\u7624\uff0c\u5305\u62ec\u809d\u7ec6\u80de\u764c\u3002\u536b\u6750\u548c<span lang=\"en-US\">PRISM<\/span>\u4e4b\u95f4\u7684\u5408\u4f5c\u7814\u7a76\u534f\u8bae\u4e2d\u89c4\u5b9a\uff0c\u57fa\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u6297\u80bf\u7624\u6d3b\u6027\u548c\u751f\u7269\u6807\u5fd7\u7269\u53d8\u5316\u7b49\u6570\u636e\uff0c<span lang=\"en-US\">POC <\/span>\u6210\u679c\u5f97\u5230\u786e\u8ba4\u3002<span lang=\"en-US\">\u00a0<\/span><\/p>\n<p>\u57fa\u4e8e<span lang=\"en-US\">POC<\/span>\u6210\u679c\uff0c\u536b\u6750\u5728\u65e5\u672c\u542f\u52a8\u4e86<span lang=\"en-US\">E7386<\/span>\u8054\u5408\u6297<span lang=\"en-US\">PD-1<\/span>\u7597\u6cd5\u5e15\u535a\u5229\u73e0\u5355\u6297\u6cbb\u7597\u5b9e\u4f53\u7624\u7684<span lang=\"en-US\">Ib\/II<\/span>\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08\u7814\u7a76<span lang=\"en-US\"> 201<\/span>\uff09\u3002<\/p>\n<p>\u536b\u6750\u9ad8\u7ea7\u526f\u603b\u88c1\u517c\u80bf\u7624\u4e1a\u52a1\u603b\u88c1<span lang=\"en-US\"> Takashi Owa <\/span>\u535a\u58eb\u8868\u793a\uff1a\u201c\u968f\u7740<span lang=\"en-US\">POC<\/span>\u6210\u679c\u7684\u786e\u8ba4\uff0c\u5411\u60a3\u8005\u63d0\u4f9b<span lang=\"en-US\">E7386<\/span>\u6cbb\u7597\u764c\u75c7\uff0c\u6211\u4eec\u5bf9\u672a\u6765\u5145\u6ee1\u4fe1\u5fc3\u3002<span lang=\"en-US\">E7386<\/span>\u53ef\u80fd\u901a\u8fc7\u4e0e\u4ed1\u4f10\u66ff\u5c3c\u6216\u5e15\u535a\u5229\u73e0\u5355\u6297\u7684\u8054\u5408\u6cbb\u7597\u6765\u514b\u670d\u4ed1\u4f10\u66ff\u5c3c\u6216\u5e15\u535a\u5229\u73e0\u5355\u6297\u7684\u6cbb\u7597\u8010\u836f\u6027\u3002\u536b\u6750\u5c06\u52a0\u5feb<span lang=\"en-US\">E7386<\/span>\u8054\u5408\u4ed1\u4f10\u66ff\u5c3c\u6216\u5e15\u535a\u5229\u73e0\u5355\u6297\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5e76\u5c3d\u6700\u5927\u52aa\u529b\u4e3a\u533b\u7597\u9700\u6c42\u672a\u5f97\u5230\u6ee1\u8db3\u7684\u764c\u75c7\u521b\u9020\u65b0\u7684\u6cbb\u7597\u65b9\u6cd5\u3002\u201d<span lang=\"en-US\">\u00a0<\/span><\/p>\n<p><span lang=\"en-US\">PRISM<\/span>\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98<span lang=\"en-US\">Dai Takehara<\/span>\u8868\u793a\uff1a\u201c<span lang=\"en-US\">E7386<\/span>\u7684\u4e34\u5e8a<span lang=\"en-US\">POC<\/span>\u7684\u6210\u679c\u8868\u660e\uff0c<span lang=\"en-US\">PRISM<\/span>\u7684\u836f\u7269\u53d1\u73b0\u5e73\u53f0\u662f\u9488\u5bf9\u88ab\u8ba4\u4e3a\u56f0\u96be\u7684\u65b0\u836f\u7269\u9776\u70b9\u7684\u6709\u6548\u9009\u62e9\u3002\u6211\u4eec\u611f\u8c22\u536b\u6750\u63a8\u52a8\u8fd9\u4e00\u53d1\u5c55\u3002\u6211\u4eec\u5c06\u7ee7\u7eed\u8fce\u63a5\u6311\u6218\uff0c\u7784\u51c6\u66f4\u591a\u65b0\u9776\u70b9\uff0c\u4e3a\u5c3d\u53ef\u80fd\u591a\u7684\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7597\u65b9\u6cd5\u3002\u201d<span lang=\"en-US\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u536b\u6750\u682a\u5f0f\u4f1a\u793e\uff08\u603b\u90e8\uff1a\u4e1c\u4eac\uff0c\u9996\u5e2d\u6267\u884c\u5b98\uff1a\u5185\u85e4\u6674\u592b\uff0c\u201c\u536b\u6750\u201d\uff09\u548c PRISM BioLab Co.\uff0cLtd.\uff08\u603b\u90e8\uff1a\u795e\u5948\u5ddd\uff0c\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\uff1aDai Takehara\uff0c\u201cPRISM\u201d\uff09\u5ba3\u5e03\uff0cCREB-\u7ed3\u5408\u86cb\u767d\uff08CBP\uff09\/\u03b2-\u8fde\u73af\u86cb\u767d\u6291\u5236\u5242E7386\uff0c\u536b\u6750\u548cPRISM\u5408\u4f5c\u7814\u7a76\u53d1\u73b0\u7684\u4e00\u79cd\u4e2d\u7b49\u5206\u5b50\u91cf\u5316\u5408\u7269\uff0c\u53d6\u5f97\u4e34\u5e8a POC\uff08\u6982\u5ff5\u9a8c\u8bc1\uff09\u3002\u00a0<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[26],"tags":[],"_links":{"self":[{"href":"https:\/\/www.9-design.net\/wp-json\/wp\/v2\/posts\/5660"}],"collection":[{"href":"https:\/\/www.9-design.net\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.9-design.net\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.9-design.net\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.9-design.net\/wp-json\/wp\/v2\/comments?post=5660"}],"version-history":[{"count":5,"href":"https:\/\/www.9-design.net\/wp-json\/wp\/v2\/posts\/5660\/revisions"}],"predecessor-version":[{"id":5668,"href":"https:\/\/www.9-design.net\/wp-json\/wp\/v2\/posts\/5660\/revisions\/5668"}],"wp:attachment":[{"href":"https:\/\/www.9-design.net\/wp-json\/wp\/v2\/media?parent=5660"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.9-design.net\/wp-json\/wp\/v2\/categories?post=5660"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.9-design.net\/wp-json\/wp\/v2\/tags?post=5660"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}<a 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